Genes annotated by the GO term GO:0006289. In nucleotide excision repair a small region of the strand surrounding the damage is removed from the DNA helix as an oligonucleotide. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase. Nucleotide excision repair recognizes a wide range of substrates, including damage caused by UV irradiation (pyrimidine dimers and 6-4 photoproducts) and chemicals (intrastrand cross-links and bulky adducts).
| PAG Title | Genes annotated by the GO term GO:0006289. In nucleotide excision repair a small region of the strand surrounding the damage is removed from the DNA helix as an oligonucleotide. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase. Nucleotide excision repair recognizes a wide range of substrates, including damage caused by UV irradiation (pyrimidine dimers and 6-4 photoproducts) and chemicals (intrastrand cross-links and bulky adducts). |
| PAG ID | TAX000440 |
| Type | A |
| Source Link |  MSigDB |
| Publication Reference | NA |
| PAG Description | |
| Species | Homo sapiens |
| Quality Metric Scores | nCoCo Score: 2,508 |
| Information Content | Rich |
| Other IDs | M12281 |
| Base PAG ID | TAX000440 |
| Human Phenotyte Annotation | |
| Curator | PAGER curation team |
| Curator Contact | PAGER-contact@googlegroups.com |
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